What is attapulgite, and how does it work (mechanism of action)? Attapulgite is an oral, nonabsorbed medication that is used in the management of diarrhea. It works by adsorbing (binding) large numbers of bacteria and toxins and reducing the loss of water. Attapulgite reduces the number of bowel movements, improves the consistency of loose or...
What is mesalamine, and how does it work (mechanism of action)? Mesalamine is a drug used for treating ulcerative colitis and mild to moderate Crohn's disease. The exact mechanism of mesalamine is not known but is believed to be by reducing inflammation in the colon. Ulcerative colitis and other inflammatory diseases cause excessive production of...
What is aluminum hydroxide/magnesium hydroxide? What is it used for? Aluminum hydroxide and magnesium hydroxide act as antacids by neutralizing stomach acid that result in an increasing pH in the stomach. Simethicone is anti-gas medication that works by lowering surface tension of gas bubbles, which gives relief from gas. What brand names are available for...
Generic drug: carglumic acid Brand name: Carbaglu What is Carbaglu (carglumic acid), and how does it work? Carbaglu (carglumic acid) is a man-made form of a liver enzyme used to treat hyperammonemia, a urea cycle disorder caused by lack of a certain liver enzyme. Carbaglu is usually given with other medications to treat this lifelong...
What is calcitriol, and how does it work (mechanism of action)? Calcitriol is a synthetic (man-made) active form of vitamin D3 (cholecalciferol). It is used to treat and prevent low levels of calcium in the blood of patients who have kidney disease or problems with their parathyroid gland, the gland that controls the amount of...
What is nizatidine, and how does it work (mechanism of action)? Nizatidine is an oral drug that blocks the action of histamine on stomach cells and reduces their production of acid. It belongs to a class of drugs called H2 blockers that also includes cimetidine (Tagamet), ranitidine (Zantac), and famotidine (Pepcid). Histamine is a naturally-occurring...
What is calcium acetate, and how does it work (mechanism of action)? Calcium acetate helps reduce phosphate levels in people with advanced kidney disease. People with advanced kidney failure retain phosphate leading to too much phosphate in their bodies (hyperphosphatemia). High phosphate levels cause hyperparathyroidism, which leads to abnormal bone formation and calcium deposits in...
What is hydrocortisone-rectal cream, ointment, and how does it work (mechanism of action)? Hydrocortisone is a natural corticosteroid produced by the adrenal glands that are located adjacent to the kidneys. Corticosteroids have potent anti-inflammatory properties and are used in a wide variety of inflammatory conditions such as: arthritis, colitis, asthma, bronchitis, certain skin rashes, and...
Generic drug: infliximab-axxq Brand name: Avsola What is Avsola (infliximab-axxq), and how does it work? Avsola (infliximab-axxq) is a prescription medicine that is approved for patients with: Rheumatoid Arthritis — adults with moderately to severely active rheumatoid arthritis, along with the medicine methotrexate. Crohn's Disease — children 6 years and older and adults with Crohn's...
What is docusate-oral, and how does it work (mechanism of action)? Docusate is a commonly used non-prescription (OTC or over-the-counter) stool softener used to treat or prevent constipation. Docusate is an anionic surfactant that helps lower the surface tension at the oil-water interface of the stool, and thus allows water and lipids or fats to...