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dopamine (Intropin) Shock Drug: Side Effects, Uses, and Dosage

Is dopamine-injection available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for dopamine-injection?

Yes

What are the uses for dopamine-injection?

What are the side effects of dopamine-injection?

Common side effects of dopamine include

Serious side effects of dopamine include

  • abnormal heart rhythm,
  • increased or decreased blood pressure,
  • increased pressure in the eye, and
  • gangrene in the extremities.

What is the dosage for dopamine-injection?

FOR ADULTS

Dopamine is given by intravenous (IV) infusion.

  • Low dose: 1 to 5 mcg/kg/minute IV to increase urine output and kidney blood
    flow.
  • Intermediate dose: 5 to 15 mcg/kg/minute IV to increase kidney blood flow,
    cardiac output and contractility, and heart rate.
  • High dose: 20 to 50 mcg/kg/minute IV to increase blood pressure and stimulate
    vasoconstriction; may increase infusion by 1 to 4 mcg/kg/minute at 10 to 30
    minute intervals until desired response (for example, adequate blood pressure)
    is achieved.

Safe and effective use of dopamine is not established in children.

Which drugs or supplements interact with dopamine-injection?

  • Dopamine should not be used in patients with
    pheochromocytoma and
    abnormal heart rate and rhythm.
  • Dopamine should not be used with medications like
    selegiline (Eldepryl,
    Zelapar),
    linezolid (Zyvox), and
    MAIO inhibitors
    like phenelzine (Nardil),
    isocarboxazid (Marplan) due to increased risk of a
    hypertensive episode.
  • Dopamine should not be used with
    tricyclic antidepressants (for example,
    amitriptyline
    [Elavil,
    Endep]) that increase dopamine and norepinephrine due to increased risk
    of hypertension and abnormal heart rate and rhythm.

Is dopamine-injection safe to take if I’m pregnant or breastfeeding?

  • There are no adequate studies done on dopamine to determine its
    safe and effective use in
    pregnant women.
  • It is not known whether dopamine enters
    breast milk;
    therefore, it is best to be cautious before using it in
    nursing mothers.

What else should I know about dopamine-injection?

What preparations of dopamine-injection are available?

  • Additive solutions for IV infusion: 40, 80, 160 mg/ml.
  • Infusion
    Solution: 80, 160, 320, mg/100 ml
How should I keep dopamine-injection stored?

Dopamine injections are stored at room temperature between 20 C to
25 C (68 F to 77 F).

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