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Targeted Therapy: Cancer Therapies Targeting the Tumor Microenvironment

What is targeted therapy for cancer? Some targeted cancer therapies aim at the pro-survival factors in the tumor microenvironment. The tumor microenvironment is the surrounding tissue, known as stroma, which provides the support for cancer's growth and survival. Targeted cancer therapy is a specialized cancer treatment with medications which target specific cellular mechanisms that give...

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What Are Opioid Equivalents and Conversions?

What are opioids? Switching patients from one opioid painkiller to another may be necessary for many reasons, whether cost, drug availability or the patient developing a tolerance. Opioid equivalents and conversions charts allow doctors to switch drugs while maintaining the same level of painkilling effectiveness and avoiding overdosing the patient. Opioids are chemical compounds with...

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Temixys HIV Medication: Drug Side Effects & Warnings

Generic drug: lamivudine and tenofovir disoproxil fumarate Brand name: Temixys What is Temixys (lamivudine and tenofovir disoproxil fumarate), and how does it work? Temixys (lamivudine and tenofovir disoproxil fumarate) is indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adult and pediatric patients weighing at...

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Xenleta (lefamulin)

What is Xenleta, and how does it work? Xenleta is a semi-synthetic antibacterial agent for oral and intravenous administration. Xenleta is indicated for the treatment of adults with community-acquired bacterial pneumonia (CABP) caused by the following susceptible microorganisms: Streptococcus pneumoniae, Staphylococcus aureus (methicillin-susceptible isolates), Haemophilus influenzae, Legionella pneumophila, Mycoplasma pneumoniae, and Chlamydophila pneumoniae. What are...

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Vyndaqel and Vyndamax for Heart Disease: Dosage & Interactions

Generic drug: tafamidis meglumine and tafamidis Brand name: Vyndaqel and Vyndamax What is Vyndaqel and Vyndamax, and how does it work? Vyndaqel and Vyndamax are prescription medicines used to treat adults with cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis (ATTR-CM) to reduce death and hospitalization related to heart problems. It is not known if Vyndaqel...

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Ziextenzo (pegfilgrastim): Side Effects, Dosage, Interactions

Generic drug: pegfilgrastim-bmez Brand name: Ziextenzo What is Ziextenzo (pegfilgrastim-bmez), and how does it work? Ziextenzo (pegfilgrastim-bmez) is a man-made form of granulocyte colony-stimulating factor (GCSF). G-CSF is a substance produced by the body. It stimulates the growth of neutrophils, a type of white blood cell important in the body’s fight against infection. Do not...

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Sesquient (fosphenytoin sodium) Seizure Medication Interactions

What is Sesquient, and how does it work? Generic drug: fosphenytoin sodium Brand name: Sesquient Sesquient (fosphenytoin sodium) is an anticonvulsant used to treat generalized tonic-clonic status epilepticus in adult patients and to prevent and treat seizures occurring during neurosurgery in adult patients and for short-term substitution for oral phenytoin in patients 2 years of...

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Sprix (ketorolac tromethamine): NSAID Side Effects & Dosage

Generic drug: ketorolac tromethamine Brand name: Sprix What is Sprix (ketorolac tromethamine), and how does it work? Sprix (ketorolac tromethamine) is a prescription medicine used to treat the symptoms of Pain. Sprix may be used alone or with other medications. Sprix belongs to a class of drugs called NSAIDs. It is not known if Sprix...

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What Does Prednisone Do to Your Body? Side Effects

What is prednisone? Prednisone belongs to a class of drugs called corticosteroids, which are a type of steroids. Prednisone reduces inflammation and allergy symptoms. For example, prednisone is commonly used to treat the inflammation of rheumatoid arthritis and allergic asthma. How does prednisone affect my body? Prednisone regulates various chemicals produced by your body that...

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Vizimpro: Non-Small Cell Lung Cancer (NSCLC) Drug Warnings

Generic drug: dacomitinib Brand name: Vizimpro What is Vizimpro (dacomitinib), and how does it work? Vizimpro (dacomitinib) is a prescription medicine used to treat non-small cell lung cancer (NSCLC) that has spread to other parts of the body (metastatic): As your first treatment if your tumor has certain types of abnormal epidermal growth factor receptor...