What is dalfampridine, Ampyra, and how does it work (mechanism of action)?
Ampyra is an oral medication used for treating multiple sclerosis
(MS). Its exact mechanism of action is unknown, but it is known to block movement of potassium between nerve cells. In animal studies Ampyra increased the conduction of nerve signals. The FDA approved Ampyra in December 1987.
What brand names are available for dalfampridine, Ampyra?
Ampyra
Is dalfampridine, Ampyra available as a generic drug?
GENERIC AVAILABLE: No.
Do I need a prescription for dalfampridine, Ampyra?
Yes.
What are the side effects of dalfampridine, Ampyra?
The most common side effect of Ampyra is urinary tract infections.
Other common side effects include:
Serious side effects of Ampyra include:
- seizures, and
- severe allergic reactions
(anaphylaxis).
People with a history of seizures should not use Ampyra.
Signs and symptoms of anaphylaxis include difficulty breathing; itching, and
swelling of the throat or tongue.
What is the dosage for dalfampridine, Ampyra?
The maximum recommended dose is 10 mg twice daily with or without food about 12 hours apart. Tablets should not be divided, crushed, chewed, or dissolved.
Which drugs or supplements interact with dalfampridine, Ampyra?
Drug interactions have not been identified for Ampyra.
Is dalfampridine, Ampyra safe to take if I’m pregnant or breastfeeding?
There are no adequate studies of Ampyra in
pregnant women.
It is not known whether Ampyra is excreted in
human milk.
What else should I know about dalfampridine, Ampyra?
What preparations of dalfampridine, Ampyra are available?
Tablet (extended release): 10 mg
How should I keep dalfampridine, Ampyra stored?
Ampyra should be stored at room temperature, 15 C to 30 C (59 F to 86 F).