What is hyaluronate injection, and how does it work (mechanism of action)? Hyaluronic acid is a natural chemical that is found in almost all species of animal and in various parts of the human body. It works as a biological lubricant, reducing friction between adjacent tissues. It is present in high amounts in joints and...
What is febuxostat, and how does it work (mechanism of action)? Febuxostat is a xanthine oxidase inhibitor used for treating gout caused by excessive levels of uric acid in the blood (hyperuricemia). Uric acid is formed from the breakdown of certain chemicals (purines) in the body. Hyperuricemia occurs when the body produces more uric acid...
What is diclofenac, and how does it work (mechanism of action)? Diclofenac belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) that are used for the treatment of mild to moderate pain, fever, and inflammation. Other members of this class include ibuprofen (Motrin), indomethacin (Indocin), nabumetone (Relafen), naproxen (Aleve) and several others. NSAIDs...
What is trigger finger? Trigger finger can cause any digits of the hand to lock when opening or closing. Trigger finger is a "snapping" or "locking" condition of any of the digits of the hand when opening or closing. Stenosing tenosynovitis is the medical term for trigger finger. What causes trigger finger? Local swelling from...
What are antinuclear antibodies? Diagram shows what pathologists see under the microscope in an ANA test We normally have antibodies in our blood that repel invaders in our bodies, such as virus and bacteria microbes. Antinuclear antibodies (ANAs) are unusual antibodies, detectable in the blood, that have the capability of binding to certain structures within...
What is azathioprine, and how does it work (mechanism of action)? Azathioprine is an immunosuppressant, that is, a drug that is used to suppress the immune system. It is used to treat patients who have undergone kidney transplantation and for diseases in which modifying the activity of the immune system is important. Azathioprine is a...
What is flurbiprofen, and how does it work (mechanism of action)? Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) effective in treating fever, pain, and inflammation in the body. It is similar to ibuprofen (Motrin or Advil), naproxen (Naprosyn), and others. As a group, NSAIDs are non-narcotic relievers of mild to moderate pain of many causes,...
What is Tofacitinib citrate (Xeljanz)? What is Xeljanz used for? Tofacitinib is an oral drug used for treating rheumatoid arthritis. It belongs to a class of drugs called Janus kinase (JAK) inhibitors. JAKs are enzymes (proteins) that regulate chemical signaling pathways that control biologic processes such as blood formation and the immune response that causes...
What are the uses for colchicine? Colchicine is used for the treatment of acute flares of gout. It also is used for treating FMF in adults and children 4 years of age or older. Other unapproved uses of colchicine include treatment of pseudogout, amyloidosis, and scleroderma. These unapproved uses of colchicine require further evaluation. What...
What is abatacept? What is abatacept used for? Abatacept is an injectable, synthetic (man-made) protein produced by recombinant DNA technology that is used for treating rheumatoid arthritis. It is an immunesuppressant, a drug that suppresses the immune system that is similar to alefacept (Amevive) and belatacept (Nulojix). The immune system is responsible for protecting the...