What is adalimumab, and how does it work (mechanism of action)? Rheumatoid arthritis Humira is indicated for reducing signs and symptoms, inducing major clinical response, inhibiting the progression of structural damage, and improving physical function in adult patients with moderately to severely active rheumatoid arthritis. HUMIRA can be used alone or in combination with methotrexate...
What is nabumetone, and how does it work (mechanism of action)? Nabumetone belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Other members of this class include ibuprofen (Motrin), indomethacin (Indocin), naproxen (Aleve) and several others. These drugs are used for the management of mild to moderate pain, fever, and inflammation. They work...
What is celecoxib? How does it work (mechanism of action)? Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID), for example, ibuprofen (Motrin), aspirin, and naproxen (Naprosyn) used to treat arthritis, pain, menstrual cramps, and colonic polyps. Prostaglandins are chemicals that are important contributors to the inflammation of arthritis that causes pain, fever, swelling and tenderness. Celecoxib...
What happens in joint replacement surgery? Joint replacement surgery involves replacing a destroyed joint with an artificial joint. In knee or hip replacement surgery, the artificial joint is made out of metal and plastic. In the case of joint replacement in the hand, the new joint is most commonly composed of silicone rubber or the...
Henoch-Schonlein purpura (HSP) facts Henoch-Schonlein purpura is a particular form of blood vessel inflammation called vasculitis. Henoch-Schonlein purpura frequently follows an infection of the throat or breathing passages, but it can be induced by certain medications. Henoch-Schonlein purpura causes skin rash, pain in the abdomen, and joint inflammation (arthritis). The treatment of Henoch-Schonlein purpura is...
Aspirin vs. NSAIDs side effects differences Aspirin is a type of nonsteroidal anti-inflammatory drug (NSAID). NSAIDs are non-narcotic pain relievers. Aspirin and other NSAIDs are used to treat pain and reduce inflammation from a variety of causes, such as headaches, injuries, arthritis, menstrual cramps, and muscle aches. NSAIDs also are used as fever reducers. Aspirin...
What brand names are available for valdecoxib? This drug has been discontinued. Brand name: Bextra
What is sulfinpyrazone, and how does it work (mechanism of action)? Sulfinpyrazone is an oral drug that is used to treat gout. Gout is caused by elevated blood levels of uric acid (hyperuricemia). Sulfinpyrazone works by increasing the excretion of uric acid in the urine thereby lowering the elevated levels of uric acid in the...
What is salsalate, and how does it work (mechanism of action)? Salsalate is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating fever, pain, and inflammation in the body. Salsalate is converted in the body to salicylic acid which is its active form and is closely related to aspirin. Other NSAIDs include ibuprofen (Motrin),...
What is rofecoxib, and how does it work (mechanism of action)? Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain, particularly the pain of osteoarthritis and menstrual cramps. Prostaglandins are chemicals that are important in promoting inflammation and its signs–pain, fever, swelling and tenderness. Rofecoxib blocks the enzyme that makes prostaglandins...