What are SGLT2 inhibitors? SGLT2 (sodium-glucose co-transporter 2) inhibitors are prescription oral medications used to treat type 2 diabetes. What generic and brand names of SGLT2 inhibitors are available in the US? Brand and generic names of SGLT2 inhibitors and combination products that contain SGLT2 inhibitors include: canagliflozin (Invokana) canagliflozin/metformin (Invokamet) canagliflozin/metformin extended release (Invokamet...
What is metoclopramide, and how does it work? Metoclopramide is a "prokinetic" drug that stimulates the muscles of the gastrointestinal tract including the muscles of the lower esophageal sphincter, stomach, and small intestine by interacting with receptors for acetylcholine and dopamine on gastrointestinal muscles and nerves. The lower esophageal sphincter, located between the esophagus and...
What is ondansetron oral disintegrating tablet, and how does it work (mechanism of action)? Ondansetron is an anti-nausea medication most often used to prevent nausea and vomiting caused by chemotherapy. Chemotherapy agents increase secretion of serotonin which stimulates serotonin (5-HT3) receptors in the brain, causing nausea and vomiting. Ondansetron works by selectively blocking serotonin (5-HT3)...
What is telmisartan, and how does it work (mechanism of action)? Telmisartan is a member of a family of drugs called angiotensin receptor blockers (ARBs), which includes losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), and candesartan (Atacand). Angiotensin, formed in the blood by the action of angiotensin converting enzyme (ACE), is a powerful chemical that attaches...
What is oral passion flower (Passiflora incarnata)? What are the uses for oral passion flower? Passion flower is a plant used for making medicine to treat several conditions. Passion flower may have effects that are similar to benzodiazepines (for example diazepam [Valium]) and monoamine oxidase inhibitors or MAOIs (for example, selegiline). Passion flower has calming,...
Facts you should know about dislocated knees Share Your Story A dislocated knee causes severe pain. Knee dislocations are a result of significant force or trauma. With a dislocated knee, the relationship between the femur and tibia is lost and at least three of four ligaments that hold the knee stable must be torn. Fractures...
Dicyclomine vs. Donnatal: What’s the difference? Dicyclomine and Donnatal (belladonna/phenobarbital) are used to treat irritable bowel syndrome (IBS). Dicyclomine and Donnatal belong to different drug classes. Dicyclomine is an anticholinergic and Donnatal is a combination of an anticholinergic/antispasmodic. A brand name for dicyclomine is Bentyl. Side effects of dicyclomine and Donnatal that are similar include...
Facts you should know about dislocated knees Share Your Story A dislocated knee causes severe pain. Knee dislocations are a result of significant force or trauma. With a dislocated knee, the relationship between the femur and tibia is lost and at least three of four ligaments that hold the knee stable must be torn. Fractures...
What are topical corticosteroids? Corticosteroid hormones are naturally occurring hormones produced by the adrenal glands within the body. Topical corticosteroids are synthetic (man-made) corticosteroid medications used for treating skin conditions such as rash, dermatitis, itching, eczema, and psoriasis. Topical corticosteroids have potent anti-inflammatory actions and also suppress the immune response. Topical corticosteroids are used based...
What is torsemide, and how does it work? Torsemide (Demadex) is a potent drug that's a diuretic (water pill). This medicine causes a profound increase in urine output (diuresis) by preventing the kidney from retaining water. Specifically, it blocks the reabsorption back into the blood of sodium and water that has been filtered out of...