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Feverfew (Tanacetum parthenium): Side Effects and Dosage

What is feverfew (tanacetum parthenium)-oral, and how does it work (mechanism of action)?

Tanacetum parthenium is an herb. The leaves are
used as a natural herbal supplement. Tanacetum parthenium contains parthenolide,
which works on serotonin receptors in the brain, giving relief from migraine
headaches. Tanacetum parthenium is also believed to have anti-inflammatory, pain
relieving, and anti-histamine effects. Check with your health-care professional
before using herbs or herbal supplements.

What brand names are available for feverfew (tanacetum parthenium)-oral?

Feverfew, Bachelor’s Buttons, Featherfew

Is feverfew (tanacetum parthenium)-oral available as a generic drug?

GENERIC AVAILABLE: Yes

Do I need a prescription for feverfew (tanacetum parthenium)-oral?

No

What are the side effects of feverfew (tanacetum parthenium)-oral?

Common side effects of Tanacetum parthenium are oral ulcers and
tongue soreness if dried leaves are chewed. It can cause increased heart rates,
dizziness, anxiety, sleeplessness, abdominal pain,
bloating, nausea, and
diarrhea.

What is the dosage for feverfew (tanacetum parthenium)-oral?

Migraine headache prevention: Take 50 – 100 mg dried leaf extract by mouth
once daily; for other preparations, see manufacturer’s directions.

Safe and effective use of Tanacetum parthenium is not established for
individuals under the age of 18.

Which drugs or supplements interact with feverfew (tanacetum parthenium)-oral?

: Tanacetum parthenium should be used with caution with
warfarin (Coumadin), clopidogrel (Plavix), and
aspirin because Tanacetum
parthenium can decrease clotting, increasing bleeding risk from these
medications.

Tanacetum parthenium may reduce break down or conversion of drugs in the
liver. Examples include omeprazole (Prilosec), lansoprazole (Prevacid),
amiodarone (Cordarone), lovastatin (Mevacor), ketoconazole (Nizoral), and
itraconazole (Sporanox). Check with your doctor before using this herbal
product.

Is feverfew (tanacetum parthenium)-oral safe to take if I’m pregnant or breastfeeding?

It is not known whether Tanacetum parthenium enters
breast
milk; It should be avoided by nursing mothers to prevent harm to the newborn.

What else should I know about feverfew (tanacetum parthenium)-oral?

What preparations of feverfew (tanacetum parthenium)-oral are available?

Tanacetum parthenium is available as oral capsules, dried leaf
extract, and as a liquid extract. Concentration of Tanacetum parthenium may vary
from product-to-product due to multiple manufacturers producing various
products.

How should I keep feverfew (tanacetum parthenium)-oral stored?

Due to multiple manufacturers making different forms of Tanacetum
parthenium, storage requirements may vary based on individual manufacturer
practices.

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