What is Zokinvy, and how does it work? Zokinvy (lonafarnib) is a farnesyltransferase inhibitor indicated in patients 12 months of age and older with a body surface area of 0.39 m2 and above to reduce risk of mortality in Hutchinson-Gilford Progeria Syndrome; and for treatment of processing-deficient progeroid laminopathies with either heterozygous LMNA mutation with progerin-like protein accumulation or homozygous...

What’s the Point of Edging?
Edging (also known as surfing, peaking, and teasing) is the practice of delaying orgasm. Edging (also known as surfing, peaking, and teasing) is the practice of delaying orgasm. It is a teasing technique essentially taking a person right to the “edge” of orgasm, then stopping, resting, and repeating the process again. Edging can be a personal practice and a therapeutic...

What Is Cayenne Pepper Used For?
Cayenne pepper has been used all over the world for adding spice and hotness to recipes. Cayenne pepper has been used all over the world for adding spice and hotness to recipes. Known by the botanical name Capsicum annuum, it occurs in two forms: green chili pepper and red chili pepper. Cayenne pepper is also known by other names such...

What Is a Contusion Injury?
A contusion also called a bruise is one of the commonest types of wounds. A contusion injury is a type of injury that occurs when there is a tear or rupture of the tiny blood vessels under the surface of the skin. The most common cause of a contusion is a blunt injury to the body part. A contusion also...

What Does the Trapezius Muscle Do?
Trapezius performs several functions that include stabilization and movement of the shoulder blade or scapula, maintain posture, and enabling movements. The trapezius is a large superficial back muscle that resembles a trapezoid in shape. It is broad, triangular, and runs at the back of the neck and upper trunk. It starts at the base of the skull and spreads downwards...

What Causes Pain in the Trapezius Muscle? Symptoms & Treatment
6 Causes of trapezius muscle pain The trapezius is a flat, triangular muscle that extends from the back of the head to the neck. It is located very close to the skin. This large, strong muscle has many actions, including the movement of the neck, arms, and shoulder blade. Trapezius or ‘trap’ muscle pain is often known as acute or...

What are the First Symptoms of Emphysema?
What is emphysema? Emphysema is a chronic lung disease that makes breathing difficult. Early symptoms include difficulty breathing, persistent cough, extreme fatigue, and more. Emphysema is a chronic lung disease that damages the alveoli, or small air sacs, in the lung. These air sacs are normally stretchy and elastic. They inflate when you inhale and deflate as you exhale. Emphysema,...

What Are the Benefits of Eating Dates?
Benefits of dates The enormous health benefits of dates have made it one of the best ingredients for the daily diet. The enormous health benefits of dates have made it one of the best ingredients for the daily diet. It is believed that consuming one date a day may be an important component for a healthy and balanced diet. This...

What Are the Signs and Symptoms of Anoxia?
What is anoxia? Anoxia symptoms include problems focusing, memory loss, poor judgment, difficulties with motor coordination, visual disturbances, decrease of executive function and impulsive behavior. Anoxia occurs when the brain is deprived of oxygen. It's often used interchangeably with hypoxia, although hypoxia refers to a partial loss of oxygen and happens first, typically leading to anoxia or a total lack...
MELAS Syndrome: Mitochondrial Disease, Symptoms & Life Expectancy
What is MELAS? MELAS is a rare genetic disorder which results in stroke and dementia. MELAS is an abbreviation that stands for Mitochondrial Encephalopathy, Lactic acidosis, and Stroke-like episodes. What causes MELAS? MELAS syndrome is caused by mutations in the genetic material (DNA) in the mitochondria. While most of our DNA is in the chromosomes in the cell nucleus, some of...