What is simethicone, and how does it work (mechanism of action)?
Simethicone is an anti-gas (anti-flatulence) medication. It acts in the stomach
and intestines to change the surface tension of gas bubbles, enabling their
breakdown and the formation of larger bubbles. In this way it is believed that
gas can be eliminated more easily by
passing flatus. Simethicone was
approved by the FDA in 1952.
Is simethicone available as a generic drug?
GENERIC AVAILABLE: Yes
Do I need a prescription for simethicone?
What are the uses for simethicone?
What are the side effects of simethicone?
Common side effects may include:
What is the dosage for simethicone?
The recommended dose for
relieving gas is 40-125 mg 4 times daily after meals and at bedtime. The drops
can be mixed with water, infant formula or other liquids for use in small
Which drugs or supplements interact with simethicone?
There are no known drug interactions with simethicone.
Is simethicone safe to take if I’m pregnant or breastfeeding?
Safety during pregnancy has not been adequately evaluated. Simethicone is generally considered safe during pregnancy because it does not cross the placenta.
Simethicone is considered safe during lactation because it is not absorbed into the body and infants are often treated with simethicone.
What else should I know about simethicone?
What preparations of simethicone are available?
Liquid drops: 40 mg per 0.6 ml. Chewable tablets: 40, 80 and 125
mg. Capsules: 125 and 180 mg.
How should I keep simethicone stored?
Preparations should be stored at room
temperature, 15 C – 30 C (59 F – 86 F).