Teflaro (ceftaroline fosamil) for Bacterial Pneumonia & Skin Infections

What is Teflaro, and how does it work?

Teflaro (ceftaroline fosamil) is a cephalosporin antibiotic used to treat skin infections or pneumonia caused by bacteria.

What are the side effects of Teflaro?

Common side effects of Teflaro include:

• nausea
• vomiting
• constipation
• diarrhea
• dizziness
• itching

Tell your doctor if you experience serious side effects of Teflaro including:

• watery or bloody diarrhea
• chest pain
• fever
• chills
• body aches
• flu symptoms
• unusual bleeding
• seizures (convulsions)
• pale skin
• dark colored urine
• confusion
• weakness
• jaundice (yellowing of the skin or eyes)
• sore throat
• headache with a severe blistering, peeling, and red skin rash
• increased thirst
• loss of appetite
• swelling
• weight gain
• feeling short of breath
• urinating less than usual or not at all
• low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling)

What is the dosage for Teflaro?

Community-Acquired Bacterial Pneumonia

• Teflaro is indicated in adult and pediatric patients 2 months of age and older for the treatment of community-acquired bacterial pneumonia (CABP) caused by susceptible isolates of the following Gram-positive and Gram-negative microorganisms:
  • Streptococcus pneumoniae (including cases with concurrent bacteremia),
  • Staphylococcus aureus (methicillin-susceptible isolates only),
  • Haemophilus influenzae,
  • Klebsiella pneumoniae,
  •  Klebsiella oxytoca, and
  • Escherichia coli.

Usage

• To reduce the development of drug-resistant bacteria and maintain the effectiveness of Teflaro and other antibacterial drugs, Teflaro should be used to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.
• Appropriate specimens for microbiological examination should be obtained in order to isolate and identify the causative pathogens and to determine their susceptibility to ceftaroline.
• When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy.
• In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Bowel regularity means a bowel movement every day.
See Answer

What drugs interact with Teflaro?

No Information provided

Is Teflaro safe to use while pregnant or breastfeeding?

• There are no adequate studies with Teflaro in pregnant women that informed any drug associated risks.
•  The background risk of major birth defects and miscarriage for the indicated population is unknown.
• The background risk of major birth defects is 2-4% and of miscarriage is 15-20% of clinically recognized pregnancies within the general population.
• No data is available regarding the presence of ceftaroline in human milk, the effects of ceftaroline on breastfed infants, or the effects on milk production.
• The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for Teflaro and any potential adverse effects on the breastfed child from Teflaro or from the underlying maternal condition.