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Mytesi (crofelemer): Diarrhea Relief for HIV/AIDS Therapy

What is Mytesi, and how does it work?

Mytesi (crofelemer delayed-release tablets) is an anti-diarrheal indicated for the symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on antiretroviral therapy.

What are the side effects of Mytesi?

Common side effects of Mytesi include:

What is the dosage for Mytesi?

  • Before starting Mytesi, rule out infectious etiologies of diarrhea.
  • The recommended adult dosage of Mytesi is 125 mg taken orally two times a day, with or without food.
  • Do not crush or chew Mytesi tablets.
  • Swallow whole.

What drugs interact with Mytesi?

Nelfinavir, Zidovudine, And Lamivudine

Is Mytesi safe to use while pregnant or breastfeeding?

  • There are no adequate, well-controlled studies in pregnant women.
  • This drug should be used during pregnancy only if clearly needed.
  • It is not known whether crofelemer is excreted in human milk.
  • Because many drugs are excreted in human milk and because of the potential for adverse reactions in nursing infants from
    Mytesi, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

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